• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Clindamycin 100 mg Pessaries are and what they are used for
2. What you need to know before you use Clindamycin 100 mg Pessaries
3. How to use Clindamycin 100 mg Pessaries
4. Possible side effects
5. How to store Clindamycin 100 mg Pessaries
6. Contents of the pack and other information

• If you are allergic to clindamycin, another antibiotic called lincomycin or to any of the other ingredients of this medicine (listed in section 6).
• If you have previously had inflammation of the colon (colitis) when taking antibiotics.

Talk to your doctor or pharmacist before using Clindamycin 100 mg Pessaries

• if you have diarrhoea or usually get diarrhoea when you take antibiotics
• if you have a history of inflammatory bowel disease such as Crohn’s Disease or Ulcerative Colitis

If you develop severe or prolonged or bloody diarrhoea during or after using Clindamycin 100 mg Pessaries consult your doctor immediately since it may be necessary to interrupt the treatment. This may be a sign of bowel inflammation (pseudomembranous colitis) which can occur following treatment with antibiotics.

Please discuss with your doctor if you can use this medicine if the following apply:

• if you suffer from problems with your kidney, liver or immune system
• if you are under 16 years old or over 65 years old.

As with all vaginal infections, sexual intercourse during treatment with Clindamycin 100 mg Pessaries is not recommended. Clindamycin 100 mg Pessaries may weaken condoms and diaphragms. Do not rely on condoms or contraceptive diaphragms when using this medicine for 72 hours following treatment.

The use of other vaginal products such as tampons or douches (vaginal washes) during treatment with the pessaries is not recommended.

Clindamycin 100 mg Pessaries are not to be used in children under 16 years old.

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. In particular tell your doctor if you are taking.

• Medicines to relax your muscles as Clindamycin 100 mg Pessaries may increase the action of such medicines.

If you are pregnant or breast-feeding, think you may be pregnant or planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

The use of Clindamycin 100 mg Pessaries in the first three months of pregnancy is not recommended as there is insufficient evidence of safety.

If you are pregnant Clindamycin 100 mg Pessaries should only be used after careful discussion with your doctor who will decide if this treatment is appropriate for you.

If you are breast-feeding your doctor will decide if Clindamycin 100 mg Pessaries are appropriate for you as the active substance may be passed into human milk.

Although it is not likely that a nursing infant will take in very much of the active substance from the milk it drinks, if your baby gets bloodstained diarrhoea or shows any signs of illness, tell your doctor at once. You should stop breast-feeding if this happens.

This medicine is not likely to affect you being able to drive and use machines.

• Remove the pessary from the strip.
• Lie on your back with your knees drawn up to your chest.
• Insert the pessary into the vagina with the tip of your third (middle) finger as far as possible without causing discomfort.

Always wash your hands before and after inserting the pessaries.

Tell your doctor. Do not use any more pessaries until your doctor tells you to.

If the forgotten pessary is just a few hours late, use it straight away.

If it is nearly time for your next pessary, miss out the forgotten one. Take your next pessary at the normal time.

Carry on using your pessaries at the usual times.

Do not take a double dose to make up for a forgotten dose.

Sometimes you may feel better after one or two days treatment. Even if you do feel better, do not stop using the pessaries until you have completed the full course of treatment.

If a pessary is eaten or swallowed contact your doctor. The pessaries are not likely to cause any harm, but your doctor will be able to give you advice on what to do.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

• The active substance is clindamycin phosphate. Each pessary contains 119 mg of clindamycin phosphate equivalent to 100 mg of clindamycin.
• The other ingredient is hard fat.

Clindamycin 100 mg Pessaries are off-white to yellowish in colour. They are supplied in white PVC- PE strips of 3 pessaries packed in a carton box.

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