The reconstituted solution should be clear and colourless.
Warning: Do not use if the PVC holder or peelable backing is damaged or broken.
Directions for preparing MIPHTEL
1. Inspect unopened PVC holder to ensure that it is intact. Peel open the holder.
2. Aseptically withdraw the entire content of the solvent ampoule into a sterile syringe. Discard ampoule.
3. Transfer the solvent from the syringe to the powder ampoule.
4. Shake gently to dissolve drug.
5. Visually inspect the reconstituted solution for particulate matter. Do not use solutions containing particulate matter.
The reconstituted solution should be slowly withdrawn from the ampoule into a suitable sterile syringe and should be administered into the anterior chamber of the eye.
The product provides 10mg/ml of acetylcholine chloride when diluted as recommended.
In most cases a satisfactory miosis, which will last approximately 20 minutes, is produced within seconds by 0.5–2ml of reconstituted solution. If a prolonged miosis is required a second application may be made.
The solution must be prepared just before use, since aqueous solutions of acetylcholine are unstable. Only clear and colourless solutions should be used.
The product is sterile until opened and should not be re-sterilised.
For single use only. Any unused solution should be discarded.